SUN1 antibody

Catalog No. ABIN7118769

This anti-SUN1 antibody is a Rabbit Polyclonal antibody detecting SUN1 in WB and ELISA. Suitable for Human.

Quick Overview for SUN1 antibody (ABIN7118769)

Target: SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SUN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-SUN1 Antibody

Purpose: SUN1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: unc-84 homolog A(C. elegans)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.1 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for SUN1

Target: SUN1 (Sad1 and UNC84 Domain Containing 1 (SUN1))

Alternative Name: SUN1

Background:

Synonyms: SUN domain-containing protein 1|Protein unc-84 homolog A|Sad1/unc-84 protein-like 1|SUN1|KIAA0810|UNC84A

Background: Component of SUN-protein-containing multivariate complexes also called LINC complexes which link the nucleoskeleton and cytoskeleton by providing versatile outer nuclear membrane attachment sites for cytoskeletal filaments. Required for interkinetic nuclear migration(INM) and essential for nucleokinesis and centrosome-nucleus coupling during radial neuronal migration in the cerebral cortex and during glial migration. Anchors chromosome movement in the prophase of meiosis and is involved in selective gene expression of coding and non-coding RNAs needed for gametogenesis. Required for telomere attachment to nuclear envelope and gametogenesis. Helps to define the distribution of nuclear pore complexes(NPCs)(By similarity). Required for efficient localization of SYNE4 in the nuclear envelope(By similarity).

Molecular Weight: 90 kDa

Gene ID: 6821

UniProt: O94901

Pathways: Maintenance of Protein Location